Tussplex DM

Generic Name: chlorpheniramine, dextromethorphan, and phenylephrine (klor feh NEER a meen, dex troe meh THOR fan, and feh nill EH frin)

Brand Names: Alka-Seltzer Plus Cold and Cough, C-Phen DM, C-Phen DM Drops, Cardec DM, Cardec DM Drops, Ceron-DM, Ceron-DM Drops, Cerose DM, Corfen-DM, CP Dec DM, CP Dec-DM Drops, De-Chlor DM, De-Chlor DR, Dec-Chlorphen DM, Dex PC, DM-PE-Chlor, Donatussin DM Drops, Ed A-Hist DM, HistadecDM, Maxiphen ADT, Mintuss DR, Nasohist-DM, Neo DM Drops, Nohist-DMX, Norel DM, P Chlor DM, PD-Cof, PD-Cof Drops, Poly-Tussin DM, Quartuss DM, Reme Tussin DM, Rondec-DM, Rondec-DM Drops, Rondex-DM, Rondex-DM Drops, Sildec-PE DM, Sildec-PE DM Drops, Tri-Vent DPC, Trital DM, Tussplex DM, Zotex-12D

What is Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, dextromethorphan, and phenylephrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Chlorpheniramine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

• kidney disease;


• liver disease;


• 
  

  diabetes;

  
  


• 
  

  glaucoma;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  diabetes;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  a stomach ulcer or a stomach obstruction,

  
  


• 
  

  emphysema or chronic bronchitis; or

  
  


• 
  

  an enlarged prostate or urination problems.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. If you use the effervescent tablet, drop the tablet in 8 ounces of water and allow it to dissolve completely. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);

  
  


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  confusion, hallucinations;

  
  


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  slow, shallow breathing;

  
  


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  urinating less than usual or not at all;

  
  


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  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  
  


• 
  

  nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  blurred vision;

  
  


• 
  

  dry mouth;

  
  


• 
  

  nausea, stomach pain, constipation;

  
  


• 
  

  mild loss of appetite, stomach upset;

  
  


• 
  

  warmth, tingling, or redness under your skin;

  
  


• 
  

  feeling excited or restless;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  restless or excitability (especially in children);

  
  


• 
  

  skin rash or itching;

  
  


• 
  

  dizziness, drowsiness;

  
  


• 
  

  problems with memory or concentration; or

  
  


• 
  

  ringing in your ears.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tussplex DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

• 
  

  an antidepressant;

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  medication to treat irritable bowel syndrome;

  
  


• 
  

  celecoxib (Celebrex);

  
  


• 
  

  cinacalcet (Sensipar);

  
  


• 
  

  imatinib (Gleevec);

  
  


• 
  

  quinidine (Quinaglute, Quinidex);

  
  


• 
  

  ranolazine (Ranexa)

  
  


• 
  

  ritonavir (Norvir);

  
  


• 
  

  sibutramine (Meridia);

  
  


• 
  

  terbinafine (Lamisil);

  
  


• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

  
  

This list is not complete and there may be other drugs that can interact with chlorpheniramine, dextromethorphan, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Tussplex DM resources

• Tussplex DM Side Effects (in more detail)
• Tussplex DM Use in Pregnancy & Breastfeeding
• Tussplex DM Drug Interactions
• Tussplex DM Support Group
• 0 Reviews for Tussplex DM - Add your own review/rating

• Bronkids Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Cardec DM Elixir MedFacts Consumer Leaflet (Wolters Kluwer)


• Ceron-DM Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Maxiphen ADT MedFacts Consumer Leaflet (Wolters Kluwer)


• Quartuss DM Prescribing Information (FDA)


• Trital DM Prescribing Information (FDA)

Compare Tussplex DM with other medications

• Cough and Nasal Congestion

Where can I get more information?

• Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

See also: Tussplex DM side effects (in more detail)

Triaminic Decongestant/Cough Infant Orally Disintegrating Strips

Pronunciation: DEX-troe-meth-OR-fan/FEN-il-EF-rin
Generic Name: Dextromethorphan/Phenylephrine
Brand Name: Examples include Triaminic Cold/Cough and Triaminic Decongestant/Cough Infant

Triaminic Decongestant/Cough Infant Orally Disintegrating Strips are used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Triaminic Decongestant/Cough Infant Orally Disintegrating Strips are a decongestant and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, which helps you to breathe more easily. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips if:

• you are allergic to any ingredient in Triaminic Decongestant/Cough Infant Orally Disintegrating Strips


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or other severe heart problems


• you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Triaminic Decongestant/Cough Infant Orally Disintegrating Strips:

Some medical conditions may interact with Triaminic Decongestant/Cough Infant Orally Disintegrating Strips. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke


• if you have a history of chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Triaminic Decongestant/Cough Infant Orally Disintegrating Strips. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of Triaminic Decongestant/Cough Infant Orally Disintegrating Strips's side effects may be increased


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Bromocriptine because the risk of its side effects may be increased by Triaminic Decongestant/Cough Infant Orally Disintegrating Strips


• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Triaminic Decongestant/Cough Infant Orally Disintegrating Strips

This may not be a complete list of all interactions that may occur. Ask your health care provider if Triaminic Decongestant/Cough Infant Orally Disintegrating Strips may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips:

Use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Triaminic Decongestant/Cough Infant Orally Disintegrating Strips by mouth with or without food.


• Do not remove the strip from the pouch until you are ready to take Triaminic Decongestant/Cough Infant Orally Disintegrating Strips. Be sure that your hands are dry when you touch the strip.


• Remove the strip from the pouch and place it onto the tongue. The strip dissolves quickly and can be swallowed with saliva. It may be taken with or without water.


• Use the strip right away after you open the pouch. Do not store it for future use.


• If you miss a dose of Triaminic Decongestant/Cough Infant Orally Disintegrating Strips and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips.

Important safety information:

• Triaminic Decongestant/Cough Infant Orally Disintegrating Strips may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not take appetite suppressants while you are taking Triaminic Decongestant/Cough Infant Orally Disintegrating Strips without checking with your doctor.


• If you have trouble sleeping, ask your pharmacist or doctor about the best time to take Triaminic Decongestant/Cough Infant Orally Disintegrating Strips.


• Triaminic Decongestant/Cough Infant Orally Disintegrating Strips has dextromethorphan and phenylephrine in it. Before you start any new prescription or nonprescription medicine, read the ingredients to see if it has dextromethorphan or phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or take Triaminic Decongestant/Cough Infant Orally Disintegrating Strips for longer than prescribed without checking with your doctor.


• Do not use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.


• If your symptoms do not improve within 5 to 7 days, if they become worse, or if they occur with fever, rash, or persistent headache, check with your doctor.


• Triaminic Decongestant/Cough Infant Orally Disintegrating Strips may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Triaminic Decongestant/Cough Infant Orally Disintegrating Strips.


• Tell your doctor or dentist that you take Triaminic Decongestant/Cough Infant Orally Disintegrating Strips before you receive any medical or dental care, emergency care, or surgery.


• Use Triaminic Decongestant/Cough Infant Orally Disintegrating Strips with caution in the ELDERLY; they may be more sensitive to its effects.


• Caution is advised when using Triaminic Decongestant/Cough Infant Orally Disintegrating Strips in CHILDREN; they may be more sensitive to its effects.


• Different brands of Triaminic Decongestant/Cough Infant Orally Disintegrating Strips may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Triaminic Decongestant/Cough Infant Orally Disintegrating Strips while you are pregnant. It is not known if Triaminic Decongestant/Cough Infant Orally Disintegrating Strips are found in breast milk. Do not breast-feed while taking Triaminic Decongestant/Cough Infant Orally Disintegrating Strips.

Possible side effects of Triaminic Decongestant/Cough Infant Orally Disintegrating Strips:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe or persistent nervousness, restlessness, or trouble sleeping; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Triaminic Decongestant/Cough Infant side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Triaminic Decongestant/Cough Infant Orally Disintegrating Strips:

Store Triaminic Decongestant/Cough Infant Orally Disintegrating Strips at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Triaminic Decongestant/Cough Infant Orally Disintegrating Strips out of the reach of children and away from pets.

General information:

• If you have any questions about Triaminic Decongestant/Cough Infant Orally Disintegrating Strips, please talk with your doctor, pharmacist, or other health care provider.


• Triaminic Decongestant/Cough Infant Orally Disintegrating Strips are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Triaminic Decongestant/Cough Infant Orally Disintegrating Strips. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Triaminic Decongestant/Cough Infant resources

• Triaminic Decongestant/Cough Infant Side Effects (in more detail)
• Triaminic Decongestant/Cough Infant Use in Pregnancy & Breastfeeding
• Triaminic Decongestant/Cough Infant Drug Interactions
• Triaminic Decongestant/Cough Infant Support Group
• 0 Reviews for Triaminic Decongestant/Cough Infant - Add your own review/rating

Compare Triaminic Decongestant/Cough Infant with other medications

• Cough and Nasal Congestion

Tronolane Suppositories

Generic Name: zinc oxide topical (ZINK OX ide)

Brand Names: ARC, Balmex, Boudreaux Butt Paste, Caldesene, Calmol-4 Suppository, Critic-Aid Skin Paste, Delazinc, Dermagran BC, Desitin, Desitin Maximum Strength Original, Desitin Rapid Relief Creamy, Diaper Rash Ointment, Diaper Relief, Dr. Smith's Diaper, Flanders Buttocks Ointment, Geri-Protect, Medi-Paste, PeriGuard, Pinxav, Rash Relief, RVPaque, Seniortopix Healix, Soothe & Cool Skin Paste, Sportz Block Dark, Sportz Block Light, Sportz Block Medium, Triple Paste, Tronolane Suppositories, Unna-Flex Elastic Unna Boot 3 inch, Unna-Flex Elastic Unna Boot 4 inch, Znlin

What is Tronolane Suppositories (zinc oxide topical)?

Zinc oxide is a mineral.

Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.

Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movements.

Zinc oxide topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Tronolane Suppositories (zinc oxide topical)?

You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.

Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.

Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.

Avoid using other medications on the areas you treat with zinc oxide unless you doctor tells you to.

What should I discuss with my health care provider before using Tronolane Suppositories (zinc oxide topical)?

You should not use this medication if you are allergic to zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.

It is not known whether zinc oxide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether zinc oxide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.

How should I use Tronolane Suppositories (zinc oxide topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Apply enough of this medication to cover the entire area to be treated. Zinc oxide often leaves a thin white residue that may not be entirely rubbed in.

To treat chapped skin, minor burn wounds, or other skin irritations, use the medication as often as needed. Apply a thin layer to the affected area and rub in gently.

To treat diaper rash, use this medication each time the diaper is changed. It is especially important to apply the medication at bedtime or whenever there will be a long period of time between diaper changes.

Keep the diaper area clean and dry to prevent worsening of skin rash. Change wet diapers as soon as possible. Allow the skin to dry thoroughly before putting on a fresh diaper.

When using the powder form of this medicine, pour the powder slowly to avoid a large puff into the air. Do not allow a baby to handle a powder bottle during use. Always close the lid after using the powder.

Zinc oxide rectal suppositories come with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after inserting a rectal suppository.

Try to empty your bowel and bladder just before using the suppository. Cleanse and dry your rectal area thoroughly.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in.

Stop using this medication and call your doctor if your condition does not improve within 7 days of treatment. Store at room temperature away from moisture and heat. Keep the tube cap tightly closed when not in use. You may store zinc oxide rectal suppositories in a refrigerator to prevent melting.

What happens if I miss a dose?

Since zinc oxide is used on an as needed basis, you are not likely to miss a dose. Using extra zinc oxide to make up a missed dose will not make the medication more effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Tronolane Suppositories (zinc oxide topical)?

Avoid getting this medication in your mouth or eyes. If this does happen, rinse with water right away. Do not use zinc oxide topical on deep skin wounds or severe burns. Get medical attention for more severe skin irritation or injury.

Tronolane Suppositories (zinc oxide topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using zinc oxide rectal suppositories if you have rectal bleeding or continued pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tronolane Suppositories (zinc oxide topical)?

Avoid applying other skin medications on the same treatment area with zinc oxide, unless your doctor has told you to.

There may be other drugs that can interact with zinc oxide topical or rectal suppositories. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Tronolane Suppositories resources

• Tronolane Suppositories Side Effects (in more detail)
• Tronolane Suppositories Use in Pregnancy & Breastfeeding
• Tronolane Suppositories Support Group
• 0 Reviews for Tronolane - Add your own review/rating

• Arcalyst Monograph (AHFS DI)


• Caldesene Topical Advanced Consumer (Micromedex) - Includes Dosage Information


• Desitin Cream MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tronolane Suppositories with other medications

• Anal Itching
• Dermatologic Lesion

Where can I get more information?

• Your pharmacist can provide more information about zinc oxide topical.

See also: Tronolane side effects (in more detail)

Tussin Pediatric Elixir

Pronunciation: sue-do-eh-FED-rin/dex-troe-meth-OR-fan
Generic Name: Pseudoephedrine/Dextromethorphan
Brand Name: Examples include Dexatrex D and Tussin Pediatric

Tussin Pediatric Elixir is used for:

Relieving congestion and cough due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Tussin Pediatric Elixir is a decongestant and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, which helps you to breathe more easily. The cough suppressant works in the brain to help decrease the cough reflex.

Do NOT use Tussin Pediatric Elixir if:

• you are allergic to any ingredient in Tussin Pediatric Elixir


• you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)


• you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tussin Pediatric Elixir:

Some medical conditions may interact with Tussin Pediatric Elixir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of glaucoma, an enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke


• if you have chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus

Some MEDICINES MAY INTERACT with Tussin Pediatric Elixir. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects from Tussin Pediatric Elixir may be increased


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Bromocriptine because the risk of side effects may be increased by Tussin Pediatric Elixir


• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Tussin Pediatric Elixir

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussin Pediatric Elixir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tussin Pediatric Elixir:

Use Tussin Pediatric Elixir as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tussin Pediatric Elixir may be taken with or without food.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Tussin Pediatric Elixir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussin Pediatric Elixir.

Important safety information:

• Tussin Pediatric Elixir may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tussin Pediatric Elixir. Using Tussin Pediatric Elixir alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Do not take appetite suppressants while you are taking Tussin Pediatric Elixir without checking with your doctor.


• Tussin Pediatric Elixir contains pseudoephedrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains pseudoephedrine. If it does or if you are uncertain, contact your doctor or pharmacist.


• Do NOT exceed the recommended dose or take Tussin Pediatric Elixir for longer than prescribed without checking with your doctor.


• If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.


• Tussin Pediatric Elixir may interfere with certain lab test results. Make sure that all of your doctors and lab personnel know that you are taking Tussin Pediatric Elixir.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Tussin Pediatric Elixir.


• Use Tussin Pediatric Elixir with caution in the ELDERLY because they may be more sensitive to its effects.


• Caution is advised when using Tussin Pediatric Elixir in CHILDREN because they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Tussin Pediatric Elixir, discuss with your doctor the benefits and risks of using Tussin Pediatric Elixir during pregnancy. It is unknown if Tussin Pediatric Elixir is excreted in breast milk. Do not breast-feed while taking Tussin Pediatric Elixir.

Possible side effects of Tussin Pediatric Elixir:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Tussin Pediatric Elixir:

Store Tussin Pediatric Elixir at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussin Pediatric Elixir out of the reach of children and away from pets.

General information:

• If you have any questions about Tussin Pediatric Elixir, please talk with your doctor, pharmacist, or other health care provider.


• Tussin Pediatric Elixir is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tussin Pediatric Elixir. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tussin Pediatric resources

• Tussin Pediatric Use in Pregnancy & Breastfeeding
• Tussin Pediatric Drug Interactions
• 0 Reviews for Tussin Pediatric - Add your own review/rating

Compare Tussin Pediatric with other medications

• Cough and Nasal Congestion

Demoxitocina

Demoxitocina may be available in the countries listed below.

Ingredient matches for Demoxitocina

Demoxytocin

Demoxitocina (DCIT) is also known as Demoxytocin (Rec.INN)

International Drug Name Search

Glossary

DCIT	Denominazione Comune Italiana
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Fluoxetina Cuve

Fluoxetina Cuve may be available in the countries listed below.

Ingredient matches for Fluoxetina Cuve

Fluoxetine

Fluoxetine hydrochloride (a derivative of Fluoxetine) is reported as an ingredient of Fluoxetina Cuve in the following countries:

• Spain

International Drug Name Search

dapsone

Generic Name: dapsone (DAP sone)

Brand Names:

What is dapsone?

Dapsone is an antiinfective medication.

Dapsone is used in the treatment of dermatitis herpetiformis (a skin condition) and leprosy (Hansen's disease).

Dapsone may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about dapsone?

In rare cases, dapsone has been associated with serious, and sometimes fatal blood and liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems. Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.

What should I discuss with my healthcare provider before taking dapsone?

Do not take dapsone without first talking to your doctor if you have

• 
  

  glucose 6-phosphate dehydrogenase (G6PD) deficiency;

  
  


• 
  

  methemoglobin reductase deficiency (hemoglobin M); or

  
  


• liver disease.

You may not be able to take dapsone, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Dapsone is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take dapsone without first talking to your doctor if you are pregnant or could become pregnant during treatment. Dapsone passes into breast milk and may affect a nursing baby. Do not take dapsone without first talking to your doctor if you are nursing a baby.

How should I take dapsone?

Take dapsone exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Taking dapsone with food may decrease stomach upset, should it occur.

It is important to take dapsone regularly to get the most benefit.

Your doctor may want you to have blood tests or other forms of monitoring during treatment with dapsone.

Store dapsone at room temperature away from moisture and heat.

See also: Dapsone dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication, unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a dapsone overdose may include nausea, vomiting, excitation, seizures, and bluish skin color.

What should I avoid while taking dapsone?

Avoid prolonged exposure to sunlight. Dapsone may increase the sensitivity of the skin to sunlight and sunburn may be more likely to occur. If exposure to the sun is unavoidable, wear a sunscreen and protective clothing.

Dapsone side effects

In rare cases, dapsone has been associated with serious, and sometimes fatal blood and/or liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems. Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions. If you experience any of the following serious side effects, seek emergency medical attention or contact your doctor immediately:

• 
  

  an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

  
  


• 
  

  bluish skin color;

  
  


• 
  

  muscle weakness;

  
  


• 
  

  numbness or tingling;

  
  


• 
  

  abdominal pain;

  
  


• 
  

  difficulty breathing;

  
  


• 
  

  dark colored urine or pale colored stools; or

  
  


• 
  

  unusual tiredness.

  
  

Other, less serious side effects may be more likely to occur. Notify your doctor if you experience

• 
  

  nausea or vomiting;

  
  


• 
  

  blurred vision;

  
  


• 
  

  ringing in the ears;

  
  


• 
  

  headache;

  
  


• 
  

  insomnia; or

  
  


• 
  

  increased sensitivity of the skin to sunlight.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Dapsone Dosing Information

Usual Adult Dose for Leprosy -- Lepromatous:

50 to 100 mg orally once a day for 2-5 years.

Usual Adult Dose for Leprosy -- Tuberculoid:

100 mg orally once a day for 6 months. Rifampin is additionally recommended to reduce the incidence of dapsone resistance. If the disease relapses, this regimen should be repeated.

Usual Adult Dose for Dermatitis Herpetiformis:

50 mg orally once a day continued on a life-long basis. Dosage may be advanced to 300 mg/day. Dosage reduction to a minimum maintenance level as soon as possible is recommended.

Usual Adult Dose for Pneumocystis Pneumonia:

100 mg orally once a day for 14 to 21 days. Used in combination with trimethoprim.

Usual Adult Dose for Pneumocystis Pneumonia Prophylaxis:

100 mg orally twice a week. Therapy should be continued on a life-long basis. The addition of pyrimethamine appears to significantly increase the activity of dapsone for PCP prophylaxis.

Usual Adult Dose for Toxoplasmosis -- Prophylaxis:

100 mg orally twice a week continued on a life-long basis.

Usual Pediatric Dose for Leprosy:

1 to 2 mg/kg (up to 100 mg) orally once a day.

Usual Pediatric Dose for Pneumocystis Pneumonia Prophylaxis:

> 1 month:
2 mg/kg/day (up to 100 mg) orally once a day.

Alternate dosing:
> 1 month:
4 mg/kg orally once weekly. Maximum dose = 200 mg.

Usual Pediatric Dose for Toxoplasmosis -- Prophylaxis:

> 1 month:

2 mg/kg/day (or 15 mg/m2) orally once a day. Maximum dose = 25 mg. Dapsone should be administered as part of combination therapy for prophylaxis of toxoplasmosis.

What other drugs will affect dapsone?

Many other drugs can interact with dapsone, especially those that may also affect the blood. Do not take any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, during treatment with dapsone without first talking to your doctor.

More dapsone resources

• Dapsone Dosage
• Dapsone Use in Pregnancy & Breastfeeding
• Drug Images
• Dapsone Drug Interactions
• Dapsone Support Group
• 6 Reviews for Dapsone - Add your own review/rating

• dapsone Advanced Consumer (Micromedex) - Includes Dosage Information


• Dapsone Prescribing Information (FDA)


• Dapsone Professional Patient Advice (Wolters Kluwer)


• Dapsone Monograph (AHFS DI)


• Dapsone MedFacts Consumer Leaflet (Wolters Kluwer)

Compare dapsone with other medications

• Bullous Pemphigoid
• Dermatitis Herpetiformis
• Leprosy
• Leprosy, Lepromatous
• Leprosy, Tuberculoid
• Leukocytoclastic Vasculitis
• Pemphigoid
• Pemphigus
• Pneumocystis Pneumonia
• Pneumocystis Pneumonia Prophylaxis
• Toxoplasmosis, Prophylaxis

Where can I get more information?

• Your pharmacist has more information about dapsone written for health professionals that you may read.